IGF-LR3

IGF-LR3 (Insulin-like Growth Factor 1, Long Arg3) is a synthetic IGF-1 analogue carrying a 13-residue N-terminal extension and an arginine swap at position 3. Together these changes sharply lower affinity for IGF-binding proteins, lengthening functional half-life and improving receptor availability — making it a workhorse in proliferation and anabolic-signalling research. Lyophilised powder, 1mg vial, ≥99% purity by HPLC, Certificate of Analysis on request. Dispatched from the UK, for research use only. Research applications Cellular proliferation and myoblast differentiation studies IGF-1 receptor binding and PI3K/Akt downstream signalling Glucose uptake and insulin-sensitivity pathway research Muscle protein synthesis and anti-catabolic mechanism work mTOR activation and comparisons against native IGF-1 Specifications Form: Lyophilised powder Purity: ≥99% (HPLC verified) Storage: −20°C, protected from light and moisture Available sizes: 1mg Certificate of Analysis: available on request